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• Man Grows New Jaw from Stem Cells

  A 65-year-old Finnish man received a new upper jaw that was grown in his abdomen using his own stem cells. Scientists had isolated stem cells from the patient’s fat, and sorted out the type of cells that could grow into bone tissue. The cells were applied to a custom jaw-shaped scaffold and implanted in his [...]

• Scientists Discover Key to Growing New Stem Cells

  Scientists at Duke University Medical Center have demonstrated they can grow human stem cells in the laboratory by blocking an enzyme that naturally triggers stem cells to mature and differentiate into specialized cells. The discovery may enable scientists to rapidly grow stem cells and transplant them into patients with blood disorders, immune defects and select genetic diseases.

• Scientists unlock mystery of embryonic stem cell signaling pathway

  A newly discovered small molecule called IQ-1 plays a key role in preventing embryonic stem cells from differentiating into one or more specific cell types, allowing them to instead continue growing and dividing indefinitely, according to research performed by a team of scientists who have recently joined the stem-cell research efforts at the Keck School of Medicine of the University of Southern California.

• Master switches found for adult blood stem cells

  Scientists have found a set of “master switches” that keep adult blood-forming stem cells in their primitive state. Unlocking the switches’ code may one day enable scientists to grow new blood cells for transplant into patients with cancer and other bone marrow disorders. The scientists located the control switches not at the gene level, but farther down the protein production line in more recently discovered forms of ribonucleic acid.

• Scientists discover new, readily available source of stem cells

  Scientists have discovered a new source of stems cells and have used them to create muscle, bone, fat, blood vessel, nerve and liver cells in the laboratory. The first report showing the isolation of broad potential stem cells from the amniotic fluid that surrounds developing embryos was published in Nature Biotechnology. “Our hope is that these cells will provide a valuable resource for tissue repair and for engineered organs as well.

• Scientists create 3-D scaffold for growing stem cells

  Stem cells grew, multiplied and differentiated into brain cells on a new three-dimensional scaffold of tiny protein fragments designed to be more like a living body than any other cell culture system. An MIT engineer and Italian colleagues will report the invention-which may one day replace the ubiquitous Petri dish for growing cells-in the Dec. 27th issue of the PLoS ONE.

• New insight into factors that drive muscle-building stem cells

  A report in the January issue of Cell Metabolism, a publication of Cell Press, provides new evidence explaining how stem cells known as satellite cells contribute to building muscles up in response to exercise. These findings could lead to treatments for reversing or improving the muscle loss that occurs in diseases such as cancer and AIDS as well as in the normal aging process.

• UC Irvine scientists find new way to sort stem cells

  UC Irvine scientists have found a new way to sort stem cells that should be quicker, easier and more cost-effective than current methods. The technique could in the future expedite therapies for people with conditions ranging from brain and spinal cord damage to Alzheimer's and Parkinson's diseases. The method uses electrodes on a tiny, inch-long glass slide to sort cells by their electric charges and has been used in cancer research.

• In a major breakthrough scientists find new way to create stem cells without embryos

  Stem cells with the capacity to form any type of tissue can be created from adult cells without destroying embryos, according to new research that suggests a way of sidestepping ethical controversy over the field. Three separate teams of scientists have used genetic trickery to wind back the biological clock of mature skin cells from mice, to give them the unlimited potential of stem cells that are normally found only in embryos.

• Scientists develop new procedure to differentiate human embryonic stem cells

  Scientists have developed a new procedure for the differentiation of human embryonic stem cells, with which they have created the first transplantable source of lung epithelial cells. The method involves the use of protein markers under the control of cell-specific promoters to convert undifferentiated human embryonic stem cells into highly-specialized cells.