Le Groupe Rossignol, qui a mis en place sa nouvelle équipe dirigeante présidée par David Morgan, présente son organisation commerciale et marketing. Le but est de mettre en oeuvre un management global de son portefeuille de marques en développant les synergies, tout en s’attachant à favoriser la spécificité et l’identité de chacune des marques Rossignol, Dynastar, Lange, Roxy et Ferrari.... lire la suite
Le Groupe Rossignol, qui a mis en place sa nouvelle equipe dirigeante presidee par David Morgan, presente son organisation commerciale et marketing. Le but est de mettre en oeuvre un management global de son portefeuille de marques en developpant les synergies, tout en s’attachant a favoriser la specificite et l’identite de chacune des marques Rossignol, Dynastar, Lange, Roxy et Ferrari.
"This shows that if you have a precise molecular understanding of a drug target you can very quickly decipher the reasons for response and failure to therapy and quickly come up with backup treatment strategies," said Sawyers, a Howard Hughes Medical Institute investigator. "Gleevec remains a spectacular step forward in the field of targeted therapy. However, some patients develop resistance to the drug after several years of therapy. These patients now have another effective option in this drug." "The main message is that this drug is extremely effective in CML patients who have failed all standard therapy including Gleevec," Sawyers said. "The basic science findings all panned out. What we predicted based on laboratory studies proved true in human trials. While there was some concern that this drug might be more toxic because it is more potent, we are delighted to find that it is very well tolerated." Sawyers said it's possible that Gleevec and Sprycel might be used together in patients with CML as a very effective one-two punch to fight cancer and battle drug resistance.
As Jon Udell commented in his article on search strategies, database querying is definitely a skill , and good searchers tend to have deep and hidden reservoirs of tacit skill that they can harness . And, as he says , like many other skills effective search can be learned.